The first paper from our BBSRC developmental proteome project is now out – a pilot study investigating the optimal approaches for label-free quantitation (Proteomics 2015)[PubMed]
The first paper from our BBSRC developmental proteome project is now out – a pilot study investigating the optimal approaches for label-free quantitation (Proteomics 2015)[PubMed]
Our Target Malaria consortium paper demonstrating how CRISPR-CAS9 can be used to drive disruption of female fertility genes is out now in Nature Biotechnology. A great job led by Tony Nolan in the Imperial College team. The advent of CRISPR-Cas9 based genome engineering has opened up many avenues for genome engineering in many organisms. A group of Drosophila researchers active in the field have published some guidance and recommendations for using gene drive systems based on our collective experiences. We highlight some of the potential problems, provide suggestions for using drive-based systems and call for transparency in the use of these systems in the laboratory. The consensus view of our group is available now in Science. Sarah’s thesis work on Dichaete and SoxN binding in different Drosophila species is now available on BioRxiv. Reveals the shared binding by both proteins is highly conserved.
Identifying targets of the Sox domain protein Dichaete in the Drosophila CNS via targeted expression of dominant negative proteins. (BMC Dev Biol) is work by Shih-Pei and Jelena exploring tissue-specific Dichaete phenotypes & gene expression responses.
We wish you all an eventful and fun filled 2013.
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