Here is a sample of some recent key publications from our lab. For a more comprehensive list, have a look at our reviews and research articles, and conference abstracts and proceedings.

See the profile on

Microarray technology in practiceby Steven Russell, Lisa A. Meadows, Roslin R. Russell.

After almost 10 years of running a microarray research facility, we decided to write a guide designed to demystify the technology and inform more biologists about this critically important experimental technique.

A book preview is available here.

El-Sharnouby S, Fischer B, Magbanua JP, Umans B, Flower R, Choo SW, Russell S, White R. (2016) Regions of very low H3K27me3 partition the Drosophila genome into topological domains. PLoS One 12:e0172725 [PubMed]  bioRxiv

Fabre B, Korona D, Groen A, Vowinckel J, Gatto L, Deery MJ, Ralser M, Russell S, Lilley KS. (2016) Analysis of the Drosophila melanogaster proteome dynamics during the embryo early development by a combination of label-free proteomics approaches. Proteomics DOI: 10.1002/pmic.201500482. [PubMed]

Lee H, Cho DY, Whitworth C, Eisman R, Phelps M, Roote J, Kaufman T, Cook K, Russell S, Przytycka T, Oliver B. (2016) Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster.  PLoS Genetics 12:e1006295 [PubMedbioRxiv

Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Gratz SJ, Golic KG, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O’Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J (2015) Safeguards for laboratory gene drive experiments. Science 349: 927-929. [PubMed]

Hammond A, Galizi R, Kyrou K, Simoni A, Siniscalchi C, Katsanos D, Gribble M, Baker D, Marois E, Russell S, Burt A, Windbichler N, Crisanti A, Nolan T. (2015) A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito vector Anopheles gambiaeNat Biotech doi:10.1038/nbt.3439

Carl SH. Russell S. (2015) Common binding by redundant group B Sox proteins is evolutionary conserved in Drosophila. BMC Genomics 16:292 [PubMed]

Lowe N, Rees JS, Roote J, Ryder E, Armean IM, Johnson G, Drummond E, Spriggs H, Drummond J, Magbanua JP, Naylor H, Sanson B, BastockR, Huelsmann S, Trovisco V, Landgraf M, Knowles-Barley S, Armstrong JD, White-Cooper H, Kyriacou C, the UK Drosophila protein trap screening consortium, Lilley KS, Russell S, St Johnston D. (2014) Analysis of the expression patterns, sub-cellular localisations and interaction partners of Drosophila proteins using a pigP protein trap libraryDevelopment 141: 3994-4005. [PubMed]

Ferrero E, Fischer B, Russell S (2014) SoxNeuro orchestrates central nervous system specification and differentiation in Drosophila and is only partially redundant with DichaeteGenome Biology 15:R74 [PubMed]

Aleksic J, Fischer B, Ferrero E, Russell S. (2013) The role of Dichaete in transcriptional regulation during Drosophila embryonic development. BMC Genomics 14: 861

Shen SP, Aleksic J, Russell S (2013) Identifying targets of the Sox domain protein Dichaete in the Drosophila CNS via targeted expression of dominant negative proteins. BMC Dev Biol 13: 1.

Housden BE, FuAQ, Krejci A, Bernard F, FischerB, Tavare S, Russell S, Bray SJ. (2013) Transcriptional dynamics elicited by a short pulse of Notch activationPLoS Genetics 9:e1003162.

Bossing T, Fischer B, Russell S, Shepherd D. (2012) Disruption of Microtubule Integrity Initiates Mitosis during CNS Repair. Dev. Cell 23: 433-440. (PubMed)

Fischer B, Wasbrough E, Meadows LA, Randlet O, Dorus S, Karr TL, Russell S. (2012) Conserved properties of Drosophila and human spermatozoal mRNA repertoiresProc. R. Soc. Lon. B. 279: 2636-2644 (PubMed)

Rees JS, Lowe N, Armena IM, Roote J, Johnson G, Drummond E, Spriggs H, Ryder E, Russell S, St Johnston D, Lilley KS (2011) In vivo analysis of proteomes and interactomes using parallel affinity capture (iPAC) coupled to mass spectrometry. Mol. Cell. Proteomics 10: M110.002386 (PubMed)

Baker DA, Nolan T, Fischer B, Pinder A, Crisanti A, Russell S. (2011) A comprehensive atlas of tissue-specific expression in the malaria vector, Anopheles gambiae, reveals genes evolved for specialized feeding and mating behaviours. BMC Genomics 12: 296 (PubMed) Accompanying commentary article

Chan YS, Naujoks, DA, Huen DS, Russell S (2011) Characterisation of a homing endonuclease based drive strategy in Drosophila melanogaster. Genetics 188: p33-44.

Choo SW, White R, Russell S.  (2011) Genome-wide analysis of the binding of the Hox protein Ultrabithorax and the Hox cofactor Homothorax in Drosophila. PLoS ONE 6: e14778

Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li R, Ishii H, Spokony RF, Chen J, Hwang L, Chen C, Auburn RP, Davis MP, Domanus M, Shah PK, Morrison CA, Zieba J, Suchy S, Senderowicz L, Victorsen A, Bild NA, Grundstad AJ, Hanley D, MacAlpine DM, Mannervik M, Venken K, Bellen H, White R, Gerstein M, Russell S, Grossman RL, Ren B, Posakony JW, Kellis M, White KP. (2011) A Cis-Regulatory Map of the Drosophila Genome. Nature 471: p527-531

The modENCODE Consortium, Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, Robine N, Washington NL, Di Stefano L, Berezikov E, Brown CD, Candeias R, Carlson JW, Carr A, Jungreis I, Marbach D, Sealfon R, Tolstorukov MY, Will S, Alekseyenko A, Artieri C, Booth B, Brooks AN, Dai Q, Davis C, Duff M, Feng X, Gorchakov A, Gu T, Henikoff J, Kapranov P, Li R, MacAlpine H, Malone J, Minoda A, Nordman J, Okamura K, Perry M, Powell S, Riddle N, Sakai A, Samsonova A, Sandler J, Schwartz Y, Sher N, Spokony R, Sturgill D, van Baren M, Wan K, Yang L, Yu C, Feingold E, Good P, Guyer M, Lowdon R, Ahmad K, Andrews J, Berger B, Brenner SE, Brent M, Cherbas L, Elgin S, Gingeras T, Grossman R, Hoskins R, Kaufman T, Kent W, Kuroda M, Orr-Weaver T, Perrimon N, Pirrotta V, Posakony J, Ren B, Russell S, Cherbas P, Graveley BR, Lewis S, Micklem G, Oliver O, Park PJ, Celniker SE, Henikoff S, Karpen GH, Lai EC, MacAlpine DM, Stein LD, White KP, Kellis M. (2010) Identification of functional elements and regulatory circuits in Drosophila modENCODE. Science 330: p1787-1797.

Meadows LA, Chan YS, Roote J, Russell S. (2010) Neighbourhood continuity is not required for correct testis gene expression in Drosophila. PLoS Biology 8:e1000552.�� (Editors Pick of the week: PLoS Biol 8:e1001002)

Nègre N, Brown CD, Shah PK, Kheradpour P, Morrison CA, Henikoff JG, Feng X, Ahmad K, Russell S, White RAH, Stein L, Henikoff S, Kellis M and KP White (2010) A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet. 6: e1000814.

Baker D.A. and Russell, S. (2009) Gene expression during Drosophila melanogaster egg development. BMC Genomics 10: 242 (Highly Accessed)

Nanda, S., Defalco, T.J., Hui Yong Loh, S., Phochanukul, N., Camara, N., Van Doren, M. and Russell, S. (2009) Sox100B, a Drosophila group E Sox-domain gene, is required for somatic testis differentiation. Sexual Dev. 3: 26-37

Kwong, C., Adryan, B., Bell, I., Meadows, L., Russell, S., Manak, J.R., White, R. (2008) Stability and dynamics of Polycomb target sites in Drosophila development. PLoS Genet. 4: e1000178

Ryder, E., Ashburner, M., Bautista-Llacer, R., Drummond, J., Webster, J., Johnson, G., Morley, T., Sang Chan, Y., Blows, F., Coulson, D., Reuter, G., Baisch, H., Apelt, C., Kauk, A., Rudolph, T., Kube, M., Klimm, M., Nickel, C., Szidonya, J., Mar��y, P., Pal, M., Rasmuson-Lestander, Å., Ekström, K., Stocker, H., Hugentobler, C., Hafen, E., Gubb, D., Pflugfelder, G., Dorner, C., Mechler, B., Schenkel, H., Marhold, J., Serras, F., Corominas, M., Punset, A., Roote, J. and S. Russell. (2007) The DrosDel Deletion Collection: A������Drosophila Genome-Wide Chromosomal Deficiency Resource. Genetics 177: 615-629 (Cover Image)