The fly genome in 3D

A fantastic paper from Giacomo Cavalli’s lab – a whole genome Hi-C map of the fly genome develops a model of the way the fly genome is partitioned into regulatory domains in the nucleus. ┬áThis is a technical tour-de-force that provides a basis for exploring how the genome is partitioned into active and inactive domains in the 3D space of the nucleus.

Sexton et al (2012) Cell 148:

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